Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter?
Background: A majority of patients with gastroesophageal reflux disease (GERD) have normal endoscopy.We aimed to investigate whether esophageal primary and secondary peristalsis influence esophageal reflux parameters in patients with normal endoscopy.Methods: We enrolled consecutive patients with typical reflux symptoms and normal endoscopy.All pat